ID   HS_ACTB     standard; single; VRT.
XX
AC   EP17045;
XX
DT   ??-NOV-1988 (Rel. 17, created)
DT   06-APR-2006 (Rel. 86, Last annotation update).
XX
DE   beta-actin.
OS   Homo sapiens (human).
XX
HG   Homology group 19; Mammalian, avian beta-actin.
AP   none.
NP   none.
XX
DR   GENOME; NT_007819.16; NT_007819; [5059193, -42631189].
DR   CLEANEX; HS_ACTB.
DR   EMBL; AC006483.3; [-169955,26461].
DR   EMBL; Y00474.1; [-2009, 2].
DR   EMBL; E06566.1; [-245, 931].
DR   EMBL; E01452.1; [-245, 931].
DR   EMBL; E01094.1; [-240, 3406].
DR   EMBL; M10277.1; [-240, 3406].
DR   EMBL; E00829.1; [-238, 2827].
DR   EMBL; AY582799.1; [-1931, 5468].
DR   SWISS-PROT; P60709; ACTB_HUMAN.
DR   TRANSFAC; R00039; HS$BAC_03; [-60, -50]; by position.
DR   TRANSFAC; R00039; HS$BAC_03; [-88, -83]; by position.
DR   TRANSFAC; R00040; HS$BAC_04; [-73, -50]; by position.
DR   RefSeq; NM_001101.
DR   MIM; 102630.
XX
RN   [1]
RX   MEDLINE; 3837182.
RA   Ng S.Y., Gunning P., Eddy R., Ponte P., Leavitt J., Shows T.,
RA   Kedes L.;
RT   "Evolution of the functional human beta-actin gene and its multi-
RT   pseudogene family: conservation of noncoding regions and
RT   chromosomal dispersion of pseudogenes.";
RL   Mol. Cell. Biol. 5:2720-2732(1985).
RN   [2]
RX   MEDLINE; 3165082.
RA   Sugiyama H., Niwa H., Makino K., Kakunaga T.;
RT   "Strong transcriptional promoter in the 5' upstream region of the
RT   human beta-actin gene.";
RL   Gene 65:135-139(1988).
XX
ME   Nuclease protection with homologous sequence ladder [1].
ME   Nuclease protection; transfected or transformed cells [2].
XX
SE   tcgagcggccgcggcggcgccctataaaacccagcggcgcgacgcgccaCCACCGCCGAG
XX
TX   6. Vertebrate promoters
TX   6.1. Chromosomal genes
TX   6.1.2. Structural proteins
TX   6.1.2.5. Contractile proteins
TX   6.1.2.5.1. Actin
XX
KW   Structural protein, Contractile protein, Multigene family.
XX
FP   Hs b'-actin         :+S  EU:NC_000007.12      1-   5536760; 17045.019
XX
DO        Experimental evidence: 3h,3#
DO        Expression/Regulation: housekeeping gene
RF        MCB5:2720      Gene65:135
//