| General information about the entry
|
|
| Entry name
|
HS_CGA
|
| Entry type
|
standard
|
| Promoter type
|
single
|
| Accession number
|
EP07106
|
| Description of the gene
|
Chorionic gonadotropin- Luteinizing hormone- Follicle stimulating hormone- Thyroid stimulating hormone -alpha.
|
| Creation date
|
??-DEC-1985 (Rel. 07)
|
| Last annotation
|
06-DEC-2004 (Rel. 81)
|
| Taxonomic division
|
VRT
|
| Organism
|
Homo sapiens (human)
|
| Keywords
|
Glycoprotein, Hormone.
|
|
| Similarities with other entries
|
|
| Homology group
|
Homology group 41; Mammalian CG/LH/FSH/TSH common alpha chain
|
| Alternative promoter
|
none.
|
| Neighbouring promoter(s)
|
none.
|
|
|
|
| GENOME
|
NT_007299.12
|
[25624994, -7875722]
|
grep: /db/ftp/epd/BED/epd109_HS_NCBI36.BED: No such file or directory
grep: /db/ftp/epd/BED/epd109_HS_NCBI36.BED: No such file or directory
HapMap
|
| DNA References
|
AL138827.16
|
[56091,-24753]
|
ENA
GenBank
DDBJ
|
AF109152.1
|
[-1638, 48]
|
ENA
GenBank
DDBJ
|
S70581.1
|
[-334, 152]
|
ENA
GenBank
DDBJ
|
J03765.1
|
[-334, 48]
|
ENA
GenBank
DDBJ
|
J00149.1
|
[-91, 152]
|
ENA
GenBank
DDBJ
|
| TRANSFAC
|
R00590
|
HS$GHA_01
|
[-182, -141]; by position
|
R00591
|
HS$GHA_03
|
[-152, -137]; by position
|
R00592
|
HS$GHA_02
|
[-143, -117]; by position
|
R00593
|
HS$GHA_05
|
[-112, -97]; by position
|
R00594
|
HS$GHA_06
|
[-104, -84]; by position
|
R02655
|
HS$GHA_08
|
[-181, -157]; by position
|
R02847
|
HS$GHA_09
|
[-125, -107]; by position
|
R03958
|
HS$GHA_11
|
[-23, -7]; by position
|
R18701
|
HS$GHA_13
|
[-181, -156]; by position
|
R19707
|
HS$GHA_14
|
[-123, -101]; by position
|
R02848
|
HS$GHA_10
|
[-84, -89]; by position
|
| REFSEQ
|
NM_000735
[ DBTSS ] |
| MIM
|
118850
|
|
|
|
| [1]
|
MEDLINE=6286817
Fiddes J.C., Goodman H.M.
"The gene encoding the common alpha subunit of the four human glycoprotein hormones"
J. Mol. Appl. Genet. 1:3-18(1981). |
| [2]
|
MEDLINE=2436226
Silver B.J., Bokar J.A., Virgin J.B., Vallen E.A., Milsted A., Nilson J.H.
"Cyclic AMP regulation of the human glycoprotein hormone alpha- subunit gene is mediated by an 18-base-pair element."
Proc. Natl. Acad. Sci. U.S.A. 84:2198-2202(1987). |
|
| Promoter-specific information
|
|
| Sequence
|
ggtggaaacactctgctggtataaaagcaggtgaggacttcattaactgCAGTTACTGAG |
| Method(s)
|
Primer extension [1]. |
| Taxonomy
|
6. Vertebrate promoters |
6.1. Chromosomal genes |
6.1.5. Hormones, growth factors, regulatory proteins |
6.1.5.3. Pituitary and placental hormones |
6.1.5.3.1. Glycoprotein hormones |
| Supplementary information
|
Expression/Regulation: placenta, pituitary;+cAMP |
|
|
|
| No 5' end distribution available |
|