The Eukaryotic Promoter Database is an annotated non-redundant collection of eukaryotic POL II promoters, for which the transcription start site has been determined experimentally. Access to promoter sequences is provided by pointers to positions in nucleotide sequence entries. The annotation part of an entry includes description of the initiation site mapping data, cross-references to other databases, and bibliographic references. EPD is structured in a way that facilitates dynamic extraction of biologically meaningful promoter subsets for comparative sequence analysis. This database contains 4806 promoters from several species.
EPDnew is a new collection of experimentally validated promoters in human, mouse and D. melanogaster genomes. Evidence came from TSS-mapping from high-throughput expreriments such as CAGE and Oligocapping. ChIP-seq experiments on H2AZ, H3K4me3, Pol-II and DNA methylation are also taken into account during the analysis. The resulting database contains 25988 promoters for the human collection, 9773 promoters for the mouse collection and 11389 promoters for the D. melanogaster collection.
Moreover, this resource allows to browse ENSEMBL annotated promoters for human, mouse and D. melanogaster genomes bringing the total number of availabe promoters to more than 200.000.